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LOUISVILLE, Ky. — Heisman favorite Lamar Jackson accounted for four touchdowns and No. 7Louisville raced to a 44-point lead at the half and breezed past North Carolina State 54-13 in ACC play.Jackson, who was replaced early in the fourth quarter, netted 355 yards and three touchdowns passing to go with 76 yards and one score on the ground. The Cardinals (6-1, 4-1) were strong on defense early, holding N.C. State’s offense to minus-1 yard on 11 plays in the first quarter.Ryan Finley passed for 236 yards and two touchdowns but was intercepted twice for the Wolfpack (4-3, 1-2).No. 3 Michigan 41, Illinois 8ANN ARBOR, Mich. — Wilton Speight passed for 253 yards and two touchdown passes to help No. 3 Michigan cruise to a 41-8 victory in Big Ten play.Karan Higdon gained 106 yards on eight carries, including a 45-yard touchdown, while De’Veon Smith rushed for 76 yards and a touchdown for Michigan (7-0, 4-0). Amara Darboh caught five passes for 99 yards.The Fighting Illini (2-5, 1-3) were forced to use their third-string quarterback Jeff George Jr. as Wes Lunt (back) and Chayce Crouch (undisclosed) did not dress. George Jr., son of the former NFL quarterback, completed four of 15 passes for 95 yards with a touchdown and interception in his first start.No. 10 Wisconsin 17, Iowa 9IOWA CITY, Iowa — Corey Clement rushed for 134 yards and one touchdown as No. 10 Wisconsin snapped a two-game losing streak by beating Iowa.Backup quarterback Bart Houston connected on a 17-yard touchdown pass to junior tight end Troy Fumagalli for Wisconsin (5-2, 2-2 Big Ten) Starting quarterback Alex Hornibrook passed for 197 yards as coach Paul Chryst incorporated both of his signal-callers into the game plan.Iowa (5-3, 2-2) was held to an anemic 2-of-13 on third down conversions by a stout Wisconsin defense. Quarterback C.J. Beathard completed 17 of 33 passes for just 153 yards.No. 22 North Carolina 35, Virginia 14CHARLOTTESVILLE, Va. — Quarterback Mitch Trubisky passed for 310 yards and two touchdowns as No. 22 North Carolina routed Virginia in ACC play.Running back Elijah Hood ran for 107 yards and a touchdown for the Tar Heels (6-2, 4-1). Bug Howard hauled in seven receptions for 109 yards and one score.Virginia quarterback Kurt Benkert managed just 126 yards through the air. Running back Taquan Mizzell rushed for 106 yards and caught seven passes for 25 yards for the Cavaliers (2-5, 1-2).